To study the mechanisms underlying developmental pattern formation in a tissue, one needs to analyze the dynamics of the regulators in time and space across the tissue of a specific architecture.This problem is essential for the developmental regulators (morphogens) that distribute over the tissues anisotropically, forming there maxima and gradient
: Some TLR agonists may up-regulate the activation of dendritic cells caused by viral antigenic peptides and antigen-specific cytotoxic T lymphocytes, which are crucial in HPV vaccine development.We investigated the ability of three TLR agonists, imiquimod, PIC and CpG, to stimulate the maturation of murine BM-DCs loaded with HPV11E7 CTL epitopes,
This study aimed to determine the suitable inactivation conditions of ultrasound and other five methods [heat, low pH, high pH, gamma irradiation and supercritical carbon dioxide (CO2)] to obtain paraprobiotics from Lactobacilus acidophilus, Lacticaseibacillus casei and Bifidobacterium animalis.The impact of each Travel Tumbler method at distinct c
Robustly delimited species are of paramount importance, the identification of which relies on our ability to discern boundaries between one species and the next.This is not difficult to do when species are very distinct from one another.However, in recently evolved lineages where putative species may have relatively few diagnostic features (e.g., s
Introduction: LEMON The use of tobacco and alcohol is increasing in developing countries like India.There is an urgent need to understand about these health risk behaviours among vulnerable population like plantation workers.The objective of the study was to screen the tea plantation workers for tobacco dependence and problem drinking Methodology: